Low blood transfusion rate after implementation of tranexamic acid for fast- track hip- and knee arthroplasty. An observational study of 5205 patients

The purpose of this study was to retrospectively evaluate the efficacy a tranexamic acid (TXA) perioperative protocol for primary hip- and knee arthroplasty, in terms allogenic blood transfusion rates. A retrospective cohort conducted included all hip arthroplasty procedures period 2014-2019. Patients who underwent surgery due trauma or revision were excluded. total amount 5205 patients eligible inclusion. Two equal weight depending doses TXA given, preoperative as an oral dose intravenously at wound closure. outcome rate. Further analysis on patient characteristics (e.g. age, gender), loss, haemoglobin (Hb) levels complication/readmission rate performed. 49 (0.9%) received transfusions. Mean distribution gender, body-mass index, American Society Anaesthesiologists score, duration surgery, type estimated Hb length stay statistically significant different between transfused not-transfused patients. incidence thromboembolic adverse events deep vein thrombosis/lung embolism) 0.5%. Low found after implementation standardized arthroplasty.